Truong Lab 

A versatile platform for locus-scale genome rewriting and verification.

R Brosh, JM Laurent, R Ordoñez, E Huang, MS Hogan, AM Hitchcock, LA Mitchell, S Pinglay, J Cadley, RD Luther, DM Truong, JD Boeke, MT Maurano. (2021). PNAS.

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Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.

MI Valencia-Sánchez, P De Ioannes, M Wang, DM Truong, R Lee, JP Armache, JD Boeke, KJ Armache. (2021). Science.

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Comprehensive scanning mutagenesis of human retrotransposon LINE-1 identifies motifs essential for function.

EM Adney, MT Ochmann, S Sil, DM Truong, P Mita, X Wang, DJ Kahler, D Fenyo, LJ Holt, JD Boeke. (2019). Genetics.

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Superloser: A Plasmid Shuffling Vector for Saccharomyces cerevisiae with Exceedingly Low Background.

MAB Haase, DM Truong, JD Boeke. (2019). G3.

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Resetting the yeast epigenome with human nucleosomes.

DM Truong, JD Boeke. (2017). Cell.

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Retrohoming of a mobile group II intron in human cells suggests how eukaryotes limit group II intron proliferation.

DM Truong, FC Hewitt, JH Hanson, X Cui, AM Lambowitz. (2015). PLOS Genetics.

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Versatile genetic assembly system (VEGAS) to assemble pathways for expression in S. cerevisiae.

LA Mitchell, J Chuang, N Agmon, C Khunsriraksakul, NA Phillips, Y Cai, DM Truong, A Veerakumar, Y Wang, M Mayorga, P Blomquist, P Sadda, Trueheart J, JD Boeke. (2015). Nucleic Acids Res.

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Enhanced group II intron retrohoming in magnesium-deficient Escherichia coli via selection of mutations in the ribozyme core.

DM Truong, DJ Sidote, R Russell, AM Lambowitz. (2013). PNAS.

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Genetic and biochemical assays reveal a key role for replication restart proteins in group II intron retrohoming.

J Yao, DM Truong, AM Lambowitz. (2013). PLOS Genetics.

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Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling.

MA Nagle, DM Truong, AV Dnyanmote, SY Ahn, SA Eraly, W Wu, SK Nigam. (2011). J Biol Chem.

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β1-Integrin is required for kidney collecting duct morphogenesis and maintenance of renal function.

W Wu, S Kitamura, DM Truong, T Rieg, V Vallon, H Sakurai, KT Bush, DR Vera, RS Ross, SK Nigam. (2009). AJP Renal Phys.

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Organic anion transporter 3 contributes to the regulation of blood pressure.

V Vallon, SA Eraly, WR Wikoff, T Rieg, G Kaler, DM Truong, SY Ahn, NR Mahapatra, SK Mahata, JA Gangoiti, W Wu, BA Barshop, G Siuzdak, SK Nigam. (2008). JASN.

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Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination.

DM Truong, G Kaler, A Khandelwal, PW Swaan, SK Nigam. (2007). J Biol Chem.

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Structural variation governs substrate specificity for organic anion transporter (OAT) homologs: potential remote sensing by OAT family members.

G Kaler, DM Truong, A Khandelwal, M Nagle, SA Eraly, PW Swaan, SK Nigam. (2007). J Biol Chem.

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Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.

G Kaler, DM Truong, DE Sweeney, DW Logan, M Nagle, W Wu, SA Eraly, SK Nigam. (2006). BBRC.

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Analyses of 5′ regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).

V Bhatnagar, G Xu, BA Hamilton, DM Truong, SA Eraly, W Wu, SK Nigam. (2006). J Hum Gen.

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Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

SA Eraly, V Vallon, DA Vaughn, JA Gangoiti, K Richter, M Nagle, JC Monte, T Rieg, DM Truong, JM Long, BA Barshop, G Kaler, SK Nigam. (2006). J Biol Chem.